Saturday, July 12, 2008
Tuesday, June 10, 2008
Tuesday, June 3, 2008
Sunday, May 11, 2008
Bujjigadu
There are a number of rumours doing the rounds in Tollywood about the story of the film. Some rumours even say the writer Madhubabu (detective Shadow fame) has provided the story for the film. But Madhubabu denied that he has provided the story for the film.
Prabhas has been struggling hard to lay his hands on the elusive big hit for a long time now. He pairs up with the sexy and in form Trisha in the film. Incidentally, this is his third film with Trisha. Their previous films were 'Varsham' and 'Pournami'.
Prabhas plays the role of a hardcore fan of superstar Rajnikanth in the film. There are many scenes that show Prabhas expressing his love and admiration for his idol. Prabhas also speaks with a Tami accent and there are also several Tamil words in the film. It is only natural as the hero is shown as being brought up in the city.
Mohan Babu is one of the finest actors in Tollywood. It is with this in mind that director Puri Jagannath requested him to take up the role in the film. When Puri went to narrate the story to Mohan Babu, asked Puri to sum up his role in one just word. Puri told him that he was a 'rascal' in the film. This was sufficient for Mohan Babu and he readily agreed to star in the film. He is playing the role of Trisha's sister.
Prabhas has been struggling hard to lay his hands on the elusive big hit for a long time now. He pairs up with the sexy and in form Trisha in the film. Incidentally, this is his third film with Trisha. Their previous films were 'Varsham' and 'Pournami'.
Prabhas plays the role of a hardcore fan of superstar Rajnikanth in the film. There are many scenes that show Prabhas expressing his love and admiration for his idol. Prabhas also speaks with a Tami accent and there are also several Tamil words in the film. It is only natural as the hero is shown as being brought up in the city.
Mohan Babu is one of the finest actors in Tollywood. It is with this in mind that director Puri Jagannath requested him to take up the role in the film. When Puri went to narrate the story to Mohan Babu, asked Puri to sum up his role in one just word. Puri told him that he was a 'rascal' in the film. This was sufficient for Mohan Babu and he readily agreed to star in the film. He is playing the role of Trisha's sister.
The name of Trisha's character in the movie is 'Chitti'. The interaction between Mohan Babu and hero Prabhas and his dialogues are the highlight of the film. Mohan Babu's excessive possessiveness of his sister, Trisha, and the related scenes have also come off very well.
Prabhas is playing an out and out mass hero in the film. His body language, dialogues and action are aimed at establishing him firmly as a popular mass hero. The film has already earned a very positive talk and it is likely to become a big hit.
Superstar Rajnikanth unveiled the audio of Bujjigau at the Andhra Club in Chennai recently. Puri has given several hits in recent times. His last two films, 'Desamuduru' with Allu Arjun and 'Chirutha' with Ram Charan were big hits. He hopes to score yet another big hit with Bujjigadu.
Sanjana, Sunil, Ali, MS Narayana, Jayaprakash Reddy, Sudha, Hema, Ajay, Subbaraju and others are among the star cast.
By all indications, Bujjigadu is a hilarious family entertainer with action, romance, fights and dance in equal measure. Get set to watch Bujjigadu on May 23.
Parugu
 Stylish Star Allu Arjun (AA) always gives something special to his fans in the midst of his shootings. Coming just one week after the release of Jalsa, the release of this audio is also meant to capture the Jalsa musical euphoria and sail along with it. All of Allu Arjun’s previous five films boast of great music, energetic dances, and most importantly memorable tunes. This is the first time AA teams up with Manisharma, the man behind Chiranjeevi many hits in the last 10 years. When Mani and Pawan Kalyan met the first time it was Khushi and the question is how is it when AA and Mani have met for the first time?–read on. Paragulu, written by Sirivennela, a solo hero number rendered effectively by Ranjith, is a high-energy song rich with techo beats. To soothe your nerves from the high energy of the previous number comes a soft love melody, Nammavemo, sung sweetly by Saketh. Right on the back of this melody comes another love melody, Hrudayam sung by Hemachandra and written by Sirivennela, that is soaked in melancholic humming and music. Yelageylaga, sung by Saindhavi and Kailash Kher and written by Anantha Sriram, is an attempt to be mass song, but it misses the beat and tune. Ranjith is back again to sing for Chandrabose’s pen in Chal Chal Challo…another active number, but nothing more to remember. Manakanna Podiche, sung by Rahul Nambiar and written by Anantha Sriram. is another solo hero song wants to be energetic, but again thats about it with nothing special to offer. Analysis: Manisharma has mastered Sound, with a capital M and S and so even though the tunes are not memorable the songs are good to listen to; thats about it. Every song has a music bit that is really communicative, beats are good, and sound is great, but alas what matters the most–the tunes–cannot be remembered after hearing the album. However, the songs carry a particular mood with them and I have a feeling they will gel well with the songs on screen. Of course, Allu Arjun will make sure that the beats and his steps are noticed.  |
Wednesday, May 7, 2008
Jalsa Stills
Trivikram Srinivas, who has the films Nuvve Nuvve and Athadu and a list of other blockbusters to his credit has turned up with yet another exciting movie for this summer, Jalsa. The story of the movie is also written by Trivikram Srinivas. Allu Arvind produces this film on Geetha Arts banner. The movie has an excellent casting consisting of Pawan Kalyan, Ileana, Parvati Melton, Kamalini Mukherjee, Prakash Raj and significant others.
Pawan Kalyan impresses his audience with his hilarious comedy and his stunning performance. His casual dressing style and body language match the moods of the film and he breathes life and credibility to his character as a college student. Ileana’s character is quite modest and she is portrayed as a girl next-door. However, she looks glamorous in the song sequences. The romantic scenes involving Pawan Kalyan and Ileana look real and their onscreen chemistry is unmatched. Kamalini Mukherjee and Parvati Melton have little to perform. Prakash Raj, Ali, Sunil and others have performed well in their respective roles.
Coming to the story of Jalsa, Sanjay Sahu played by Pawan Kalyan is the son of a farmer. After the loss of his brother, who dies of heart disease and his parents, who commit suicide after a crop loss, he joins the Naxalites and starts retaliating against the society. After a fierce encounter, Sanjay surrenders to police and continues his education.
At college, he meets Indu (Kamalini Mukherjee) who is the daughter of a police officer (Prakash Raj) and falls in love with her. He fails to convince the police officer and Indu gets married to an NRI. Here, Jyotsna (Parvati Melton) and Bhagmati (Ileana) enter into the scene. Both the girls try to win his love, but Bhagmati finally succeeds. Her father does not give his consent as he knows well that Sanjay is a Naxalite turned into a student.
At this point, Damodar Reddy (Mukhesh Rushi) comes into the picture to take vengeance on Sanjay for thrashing his second son. Damodar Reddy puts a spot to Bhagmati and fixes her marriage with his second son. Was Sanjay able to express his love to Bhagmati and did he succeed in winning her father’s consent, does he put a stop to Damodar Reddy, the answers to all this form the climax of the film.
The film has one of the best action scenes choreographed by Vijay that makes it a true Pawan Kalyan and Trivikram Srinivas film. Camera work by Guhan and Rasool is first-class.
On the whole, Jalsa has all the necessary ingredients in it to become a good hit. The film goes well with class and mass audience too. Also, it is not an exaggeration to say that Jalsa is a gift to the viewers for this summer. So, if you are looking out for a film which entertains then this is the one!
What others say:
Kurupati Raju a member of Sulekha.com says, “The film has nearly seven fights and one amazing scene involving a knife fight, which is a big hit. Jalsa is a must-see movie for the summer vacation”
Indiaglitz says, “The film is a mixture of comedy, emotions and much more. One can watch 'Jalsa' and have your money's worth if you are the type that enjoys films with out the element of logic. It sure is your money's worth!
Thursday, April 10, 2008
Britney Spears
What has become of our little Britney Spears? The once innocent school girl who was the fastest rising pop star in music is now the sex-addicted slut who wears t-shirts with sayings like “Virgin (But this is an Old Shirt)” and has now become an inside joke amongst crowds and an easy target for tabloid magazines looking to exploit her recent chain of bad decisions. Born in 1981 in Kentwood, Louisiana, Britney has been lighting up the stage since she made her stake as a “Star Search” contestant at only eight-years-old. She didn’t win, but she did nail an audition for the new “Mickey Mouse Club” variety show three years later, joining the ranks of fellow Mouseketeers and soon-to-be stars Keri Russell, Christina Aguilera, Justin Timberlake and Ryan Gosling for two years before the show’s eventual cancellation. Britney returned back home to a normal life after the show’s last episode and enrolled at her local high school, but the dreams she had of leaving the small town to pursue a musical career weren’t sidetracked for too long. Before she knew it, Britney was saying her goodbyes to high school friends and packing her bags for New York City with one thing on her mind: a major record label contract. She quickly signed with Jive Records and began promoting her first album, …Baby One More Time, on tiny stages in the middle of local malls for crowds of less than a hundred before her first single, “Hit Me Baby, One More Time” hit the airwaves and the lyrical farm girl was transformed into the newest pop princess on the market. The album went platinum in no time, with the help of other hits like “Crazy” and “Sometimes,” and Britney became an instant star.Following numerous tabloid stories attempting to knock the young singer off of her pedestal, Britney released her second album in 2000, Oops!...I Did It Again, to mobs of awaiting fans. The Britney craze was in full swing and the humble princess fast became the Queen of Pop with sold out shows, respect from the music critics and a million-dollar contract with Pepsi. A year later, after countless news stories of her ongoing feud with Christina Aguilera and hush-hush relationship with ‘NSYNC front man, Justin Timberlake, Britney released her third and self-titled album. While Britney continued to rise with the success of her third LP, the pop star also began to lose a lot of her younger fans when she ripped off the schoolgirl gear and pranced around in skimpy underwear with giant snakes wrapped around her neck. In what appeared to be a desperate attempt to reach out to the under-18 girls that continued to swarm the streets of Times Square and vote for their Most Requested Video, Britney released her first feature film, “Crossroads,” to newspapers filled with bad reviews and a Razzie Award for Worst Actress
Britney continued to display her rebellious, “I’m Not a Girl, Not Yet a Woman” attitude when she began popping up in People and US magazines as a wild party girl who was no longer promoting herself as the momma’s girl she claimed to be. With her fourth and most recent album, In the Zone, Britney dumped the pop sound from her past albums in place of an experimental beat that was supposed to prove to critics that she had matured as an artist. The merely decent album wasn’t what everyone was talking about in 2003 though, but rather it was the infamous onstage kiss that she shared with Madonna during MTV’s Video Music Awards. If the luscious lip-lock wasn’t enough for trigger-happy photographers and juicy magazine articles, Britney’s 55-hour Vegas marriage to friend Jason Alexander (not George of “Seinfeld’) was one of the biggest news events of the year. Now that Britney has replaced the good girl image with a tabloid-led lifestyle of dirty secrets and an untamed nightlife, we beg to gamble on how much longer this self-styled princess has before she expires.
Britney Says
On her favorite songs:
"I always listen to 'NSYNC's 'Tearin' Up My Heart.' It reminds me to wear a bra. "
On rumors that she had a breast enlargement:
"I did not have implants, I just had a growth spurt."
On the perks of being a singer:
"I get to go to lots of overseas places, like Canada."
On her new image:
"I've turned from a little nice school girl, into this sexy, slutty seductress. And I like it... I like it a lot."
Migraine Headache 5
Medical literature is full of examples of how natural hormones effect migraine headaches. As early as 1953, the British Medical Journal published Dr. Kathleen Dalton’s first hand account of how her own menstrual migraines were relieved by injections of natural hormones. This same doctor started using this therapy on her own patients, claiming an 83% success rate.
In July of 1983, Dr. Penny Budoff, writing in the Journal of Reproductive Medicine, cited successful trials of natural hormone therapy dating back to 1964, showing alleviation of multiple symptoms, including migraine headaches. She later went on to describe a Boston clinic that offered natural hormone treatments, saying they “provided effective therapy.”
There was some controversy about her findings, probably related to disagreement over how the actual hormones were introduced into the body - intramuscular, intravenous, orally or also by vaginal suppositories. There was even controversy over the dosages required. Apparently, how the treatment is given affects the overall outcomes and results.
In 2000, The Mayo Clinic announced the usage of a new type of natural hormone by one of their leading endocrinologists - Lorraine Fitzpatrick, M.D. The conclusions were natural hormones can improve the quality of life for post-menopausal women, such as decreasing the risk of endometrial cancers, sleep disorders, hot flashes, anxiety and symptoms of depression. This same study was also published in the Journal of Women’s Health.
Neuroprotective Effects
Dr. Donald Stein, with Emory University School of Medicine noted in the June, 2005, Annals of New York Academy of Sciences, that natural hormones:
“may be a potent neuroprotective agent especially in the treatment of traumatic brain injury, stroke, and certain neurodegenerative disorders.”
He continued:
“The literature surrounding [natural hormones] influence on mood, cognition, and memory in healthy subjects is not very large,”
but in general he found natural hormones do indeed offer helpful treatments in humans.
Citing animal model studies, natural hormones consistently demonstrated “beneficial effects.” Among these benefits are substantially reducing edema (swelling) in the brain as well as effectively reducing free radical damage. They also decrease brain damaged areas following a loss of blood supply and reduce nerve cell injury after a nerve contusions.
Natural hormones have anti-seizure properties and are the subject of two NIH funded clinical trials for natural hormone treatment of epilepsy in women. Finally, Dr. Stein notes natural hormones “have the potential to enhance neuronal (nerve cell) repair.”
The Annals of the New York Academy of Science in 2005 published a study by Dr. M. Singh stating that ovarian (sex) hormones:
“…can no longer be considered strictly within the confines of reproductive function, and the brain is just as important a target for hormone function.”
He goes on to write: “Indeed, recent evidence supports the neuroprotective potential of [sex hormones] itself.”
Migraines and Seizures
Dr. Andrew Herzog of the Harvard Medical School’s Neuroendocrine Unit published two articles in the journal Neurology, describing how natural hormones influence nerve cells in the brain by demonstrating a dramatic reduction (68%) in a condition called Catamenial Seizures.
These seizures paralleled the time course of migraine headaches during the menstrual cycle so closely, that the seizures are now labeled as “menstrual seizures”.
Dr. Vincent T. Martin, University of Cincinnati College of Medicine, Department of Internal Medicine, is the WORLD’S FOREMOST AUTHORITY on the relationship of migraine headaches with sex hormones. In October of 2005 he wrote that “…migraine headache and epilepsy may show a similar pattern of response to changes in ovarian hormone encountered during the menstrual cycle. …”
Describing hormonal interventions in women during their menstrual cycle, Dr. martin wrote:
”If ovarian hormones played no role in the headaches of these women, then hormonal manipulations would be expected to have no effect.”
But when hormones were added back – headaches did improve - even when measured and compared against a placebo.
Dr. Martin further wrote, “Our study also suggests that [ovarian hormones] modulate migraine headaches.” Additionally, the doctor indicated: “…the presence of [natural hormones] provided a preventative benefit for migraine headaches.”
He theorizes that natural hormones produced this benefit by enhancing a brain neurotransmitter called GABA. An increase in the GABA receptors helps suppress electrical stimulation in the trigeminal ganglion in the brain - thought to play a major role in activation of pain sensation in migraine headaches.
New Research
More recently, in special issues of this year’s journal Headache, Dr. Martin published two more review articles on ovarian hormones and migraine headaches. He opened the review with:
“Ovarian hormones have a profound influence on the central nervous system of women.” This is followed by “Migraine headache in particular appears to be strongly affected by ovarian hormones.”
His team noted that in the brain ovarian hormones are converted into metabolites, enhancing their effects. Some of the metabolites found in the brain have 100 times the concentration than found in the rest of the body.
Dr. Martin observed: “Therefore, substantial clinical evidence suggests that changes in ovarian hormones affect migraine headaches.”
The Serotonin System
In Part 2 of the review, Dr. Martin writes: “Migraine headaches are likely influenced by the different “hormonal milieus (situations)” encountered during reproductive life events that begin during menarche (first periods) and continue through menopause.”
Once inside the brain, ovarian hormones “have a prominent effect” on various neurotransmitter systems, including the serotonin and GABA systems. Again from Dr. Martin:
“Substantial evidence exists to suggest that the serotonergic system is important in the pathogenesis of migraine headache.”
Triptan medications (Imitrex, Maxalt, Zomig, etc.) enhance the action of the hormone serotonin, and are, according to Dr. Martin:
“efficacious abortive treatments for migraine headache.” “Because ovarian [hormones] play a critical role in serotonin synthesis, reuptake, and degradation they could theoretically affect migraine through their action on the serotonergic system.”
The GABA System
As Dr. Martin describes, this is a complex issue.
“GABA is the major inhibitory neurotransmitter within the central nervous system. GABAergic neurons are strongly modulated by ovarian [hormones].”
“The effect of ovarian hormones on neurotransmitter systems may be dependent on a number of variables.”
“The pathophysiology of migraine headache is a complex, but probably involves activation of a number of different “pain processing networks” within the central nervous system…” “Ovarian hormones … modulate these structures/pathways to increase or decrease the frequency, severity or duration of migraine headache.”
He cites an animal model study of migraine headaches where the brain’s main pain firing network (the trigeminal nucleus) is electrically activated. Observable symptoms decreased by 42% when pretreated with a natural hormone metabolite.
Leakage of neurotransmitter stimulators, known to cause headaches, were also suppressed as well. This was thought to be caused by the natural hormone’s ability to regulate the nerves GABA receptors.
Autonomic Nervous System
“There is evidence that the sympathetic nervous system is involved in the pathophysiology of migraine headache.” Dr. Martin
Ten to fifteen percent of patients with migraine headaches have a condition called Horner Syndrome during their headache-free periods.
Horner Syndrome is a weakness in the sympathetic nervous system. Abnormally weak eyelid muscles and the pupil causes these people to respond to light differently than those non-afflicted with this disease.
Changing the mix of ovarian hormones has actually been shown to improve this condition.
Vascular Effects
One of the most observed properties of migraine headaches has been the abnormally increased blood flow through brain arteries (vasodilation). Certain ovarian hormones counteract this effect - thereby relieving the condition.
Estrogen Withdrawal Theory
Dr. Martin stated in all of his articles:
“The most plausible theory to explain the pathophysiology of menstrual migraine is that of “excess withdrawal” of estrogen.”
When high circulating levels of estrogen are suddenly withdrawn or dropped – a migraine can occur. This has been supported by other studies as well. Migraines were induced by adding excessive estrogen early on in the menstrual cycle – then suddenly stopping it.
However, when estrogen was added later in the cycle, migraines were not suppressed. Only the onset of the next headache was delayed. As Dr. Martin noted:
“Estrogen in particular appears to modulate the frequency, severity, and disability of migraine headache.”
Other systems also had to be involved, including prostaglandins, magnesium, alterations of neurotransmitters (serotonin, GABA, opiates), sympathetic nervous system, and of course, birth control pills.
What We Can Conclude
Through Dr. Martin’s groundbreaking research, it’s obvious the right mix of ovarian hormones is crucial in maintaining a migraine free life. Too little ovarian hormones in the body – and the risk of getting a migraine greatly increases. Returning the body’s balance often reverses the situation – meaning no more migraine headaches – and no more pain.
Supplementing the body’s deficiencies with bio-identical hormones and returning the natural balance is a critical part in effectively treating and curing migraine headaches.
a migraine cure certainly eliminates the migraine nausea altogether - and concern over the ensuing migraine headache may no longer be necessary – at least in women.
APPLIES TO:
• migraine
• migraines
• migraine headaches
• headaches
• migraine headache
• migraine headache relief
• migraine relief
• headache treatment cure
• women's health
• birth control pills
• oral contraceptives
In July of 1983, Dr. Penny Budoff, writing in the Journal of Reproductive Medicine, cited successful trials of natural hormone therapy dating back to 1964, showing alleviation of multiple symptoms, including migraine headaches. She later went on to describe a Boston clinic that offered natural hormone treatments, saying they “provided effective therapy.”
There was some controversy about her findings, probably related to disagreement over how the actual hormones were introduced into the body - intramuscular, intravenous, orally or also by vaginal suppositories. There was even controversy over the dosages required. Apparently, how the treatment is given affects the overall outcomes and results.
In 2000, The Mayo Clinic announced the usage of a new type of natural hormone by one of their leading endocrinologists - Lorraine Fitzpatrick, M.D. The conclusions were natural hormones can improve the quality of life for post-menopausal women, such as decreasing the risk of endometrial cancers, sleep disorders, hot flashes, anxiety and symptoms of depression. This same study was also published in the Journal of Women’s Health.
Neuroprotective Effects
Dr. Donald Stein, with Emory University School of Medicine noted in the June, 2005, Annals of New York Academy of Sciences, that natural hormones:
“may be a potent neuroprotective agent especially in the treatment of traumatic brain injury, stroke, and certain neurodegenerative disorders.”
He continued:
“The literature surrounding [natural hormones] influence on mood, cognition, and memory in healthy subjects is not very large,”
but in general he found natural hormones do indeed offer helpful treatments in humans.
Citing animal model studies, natural hormones consistently demonstrated “beneficial effects.” Among these benefits are substantially reducing edema (swelling) in the brain as well as effectively reducing free radical damage. They also decrease brain damaged areas following a loss of blood supply and reduce nerve cell injury after a nerve contusions.
Natural hormones have anti-seizure properties and are the subject of two NIH funded clinical trials for natural hormone treatment of epilepsy in women. Finally, Dr. Stein notes natural hormones “have the potential to enhance neuronal (nerve cell) repair.”
The Annals of the New York Academy of Science in 2005 published a study by Dr. M. Singh stating that ovarian (sex) hormones:
“…can no longer be considered strictly within the confines of reproductive function, and the brain is just as important a target for hormone function.”
He goes on to write: “Indeed, recent evidence supports the neuroprotective potential of [sex hormones] itself.”
Migraines and Seizures
Dr. Andrew Herzog of the Harvard Medical School’s Neuroendocrine Unit published two articles in the journal Neurology, describing how natural hormones influence nerve cells in the brain by demonstrating a dramatic reduction (68%) in a condition called Catamenial Seizures.
These seizures paralleled the time course of migraine headaches during the menstrual cycle so closely, that the seizures are now labeled as “menstrual seizures”.
Dr. Vincent T. Martin, University of Cincinnati College of Medicine, Department of Internal Medicine, is the WORLD’S FOREMOST AUTHORITY on the relationship of migraine headaches with sex hormones. In October of 2005 he wrote that “…migraine headache and epilepsy may show a similar pattern of response to changes in ovarian hormone encountered during the menstrual cycle. …”
Describing hormonal interventions in women during their menstrual cycle, Dr. martin wrote:
”If ovarian hormones played no role in the headaches of these women, then hormonal manipulations would be expected to have no effect.”
But when hormones were added back – headaches did improve - even when measured and compared against a placebo.
Dr. Martin further wrote, “Our study also suggests that [ovarian hormones] modulate migraine headaches.” Additionally, the doctor indicated: “…the presence of [natural hormones] provided a preventative benefit for migraine headaches.”
He theorizes that natural hormones produced this benefit by enhancing a brain neurotransmitter called GABA. An increase in the GABA receptors helps suppress electrical stimulation in the trigeminal ganglion in the brain - thought to play a major role in activation of pain sensation in migraine headaches.
New Research
More recently, in special issues of this year’s journal Headache, Dr. Martin published two more review articles on ovarian hormones and migraine headaches. He opened the review with:
“Ovarian hormones have a profound influence on the central nervous system of women.” This is followed by “Migraine headache in particular appears to be strongly affected by ovarian hormones.”
His team noted that in the brain ovarian hormones are converted into metabolites, enhancing their effects. Some of the metabolites found in the brain have 100 times the concentration than found in the rest of the body.
Dr. Martin observed: “Therefore, substantial clinical evidence suggests that changes in ovarian hormones affect migraine headaches.”
The Serotonin System
In Part 2 of the review, Dr. Martin writes: “Migraine headaches are likely influenced by the different “hormonal milieus (situations)” encountered during reproductive life events that begin during menarche (first periods) and continue through menopause.”
Once inside the brain, ovarian hormones “have a prominent effect” on various neurotransmitter systems, including the serotonin and GABA systems. Again from Dr. Martin:
“Substantial evidence exists to suggest that the serotonergic system is important in the pathogenesis of migraine headache.”
Triptan medications (Imitrex, Maxalt, Zomig, etc.) enhance the action of the hormone serotonin, and are, according to Dr. Martin:
“efficacious abortive treatments for migraine headache.” “Because ovarian [hormones] play a critical role in serotonin synthesis, reuptake, and degradation they could theoretically affect migraine through their action on the serotonergic system.”
The GABA System
As Dr. Martin describes, this is a complex issue.
“GABA is the major inhibitory neurotransmitter within the central nervous system. GABAergic neurons are strongly modulated by ovarian [hormones].”
“The effect of ovarian hormones on neurotransmitter systems may be dependent on a number of variables.”
“The pathophysiology of migraine headache is a complex, but probably involves activation of a number of different “pain processing networks” within the central nervous system…” “Ovarian hormones … modulate these structures/pathways to increase or decrease the frequency, severity or duration of migraine headache.”
He cites an animal model study of migraine headaches where the brain’s main pain firing network (the trigeminal nucleus) is electrically activated. Observable symptoms decreased by 42% when pretreated with a natural hormone metabolite.
Leakage of neurotransmitter stimulators, known to cause headaches, were also suppressed as well. This was thought to be caused by the natural hormone’s ability to regulate the nerves GABA receptors.
Autonomic Nervous System
“There is evidence that the sympathetic nervous system is involved in the pathophysiology of migraine headache.” Dr. Martin
Ten to fifteen percent of patients with migraine headaches have a condition called Horner Syndrome during their headache-free periods.
Horner Syndrome is a weakness in the sympathetic nervous system. Abnormally weak eyelid muscles and the pupil causes these people to respond to light differently than those non-afflicted with this disease.
Changing the mix of ovarian hormones has actually been shown to improve this condition.
Vascular Effects
One of the most observed properties of migraine headaches has been the abnormally increased blood flow through brain arteries (vasodilation). Certain ovarian hormones counteract this effect - thereby relieving the condition.
Estrogen Withdrawal Theory
Dr. Martin stated in all of his articles:
“The most plausible theory to explain the pathophysiology of menstrual migraine is that of “excess withdrawal” of estrogen.”
When high circulating levels of estrogen are suddenly withdrawn or dropped – a migraine can occur. This has been supported by other studies as well. Migraines were induced by adding excessive estrogen early on in the menstrual cycle – then suddenly stopping it.
However, when estrogen was added later in the cycle, migraines were not suppressed. Only the onset of the next headache was delayed. As Dr. Martin noted:
“Estrogen in particular appears to modulate the frequency, severity, and disability of migraine headache.”
Other systems also had to be involved, including prostaglandins, magnesium, alterations of neurotransmitters (serotonin, GABA, opiates), sympathetic nervous system, and of course, birth control pills.
What We Can Conclude
Through Dr. Martin’s groundbreaking research, it’s obvious the right mix of ovarian hormones is crucial in maintaining a migraine free life. Too little ovarian hormones in the body – and the risk of getting a migraine greatly increases. Returning the body’s balance often reverses the situation – meaning no more migraine headaches – and no more pain.
Supplementing the body’s deficiencies with bio-identical hormones and returning the natural balance is a critical part in effectively treating and curing migraine headaches.
a migraine cure certainly eliminates the migraine nausea altogether - and concern over the ensuing migraine headache may no longer be necessary – at least in women.
APPLIES TO:
• migraine
• migraines
• migraine headaches
• headaches
• migraine headache
• migraine headache relief
• migraine relief
• headache treatment cure
• women's health
• birth control pills
• oral contraceptives
Migraine Headaches 4
Vertigo, which is an illusion of movement in relation to the environment, is commonly experienced as part of a migraine headache.
Migraine is a disease characterized by periodic headaches, but patients often experience other symptoms, including dizziness. In some patients, dizziness can be the only symptom. The dizziness associated with migraines is called vertigo.
Vertigo is basically a sensation of a room spinning around you, while at rest. Nausea and sometimes vomiting is always associated with vertigo.
Motion sickness is a common migraine accompaniment as well. Most studies report about 50% of patients with migraines have motion sickness. Patients with migraine-associated vertigo often provide a long history of motion intolerance during car, boat, or air travel or all three. People with migraines are, in general, more sensitive to motion of the environment and to busy environments.
The symptoms of migraine-associated vertigo are variable and may feel like a room spinning at rest (true vertigo), a constant feeling of imbalance, and/or dizziness associated primarily when moving and not at rest. Symptoms directly associated with a migraine headache can occur prior to the onset of headache or during a headache.
Vertigo Without Headaches
It is also quite common to experience vertigo during a headache-free interval. As such, many patients who experience migraine-associated vertigo will experience dizziness as the main symptom even in the absence of a headache! In fact, most patients with migraine-associated vertigo have dizziness that occurs independently of the headache.
This last condition of someone experiencing vertigo without any headache confuses doctors and patients alike. It is far more common than thought and most of the time is a missed diagnosis and thereby a missed opportunity for treatment.
Prevalence of Migraine-Associated Vertigo
Reports indicate that 27-42% of all migraine patients report episodic vertigo. What is interesting is that about a third (about 36%) of these patients experienced vertigo during headache-free periods. The remainder experienced vertigo either just before or during the headache. The incidence of vertigo during the headache period was higher in patients with aura as opposed to those without aura.
Duration:
The vertigo symptoms may last for a few minutes or may be continuous for several weeks or even for months! In women, there is a strong association of dizziness occurring within the menstrual cycle.
The duration of the vertigo can also be quite variable. The frequencies of different durations of vertigo spells in migraine-associated vertigo are as follows:
o 7% experience vertigo for a duration of seconds.
o 31% experience vertigo for minutes to up to 2 hours.
o 5% have vertigo for 2-6 hours.
o 8% have vertigo for 6-24 hours.
o 49% experience vertigo for longer than 24 hours.
What Causes the Vertigo Associated with Migraines?
The most commonly accepted theory regarding the pathophysiology of migraine-associated vertigo is the Cortical Spreading Depression theory (CSD). Multiple authors propose that episodes of dizziness are similar to that of a migraine aura or are actually part of the aura.
But since only about 20% of migraine sufferers actually experience an aura, researches attribute the vertigo as part of a fluctuation of nerve cell ion channels. Recent understandings in a particular type of migraine – Familial Hemiplegic Migraine (FHM) have shown two genes responsible for controlling ion flow across nerve cell membranes.
These two genes affect changes in calcium, sodium and potassium channels. This alters the electrical conduction potentials of nerve cells. The result is a transient wave front that suppresses central neuronal activity. This depression spreads in all directions from its site of origin. These changes result in a reduction in cerebral blood flow in the areas of spreading depression.
Two authors have suggested that when dizziness is unrelated to headache, the dizziness occurs from the release of neuropeptides, including substance P, neurokinin A, calcitonin and gene–related peptide [CGRP].
No single hypothesis explains the headache or dizziness process in migraine at this time. Thus, the causes of the symptoms of migraine remain controversial.
Meniere’s Disease
There is another relatively common form of vertigo called Meniere’s Disease. Meniere’s Disease is not related to migraines at all. It has a classic triad of vertigo, hearing loss and tinnitus (ringing of the ears). The vertigo of Meniere’s Disease is frequently confused with migraine-associated vertigo.
Fortunately, the vertigo associated with the more common forms of migraines rarely have any hearing loss and also does not have much in the way of tinnitus.
Basilar Migraines
The is one ominous variant of migraine headaches called Basilar Migraines (or also known as Bickerstaff ‘s syndrome) which is a cross between a migraine and occasionally ends up in a stroke. Some features of Basilar Migraines include vertigo, hearing loss and tinnitus. Up to 80% of patients with Basilar Migraine have been reported to have sensorineural hearing loss.
So in the case of the Basilar Migraines, the vertigo might be indistinguishable from Meniere’s Disease during the headache-free intervals. Otherwise the presence of the headache would lend it toward the migraine component and should be treated as a migraine.
Clearly, Basilar Migraines are a more pernicious variety of migraine headache. Even though Basilar Migraines are classified as a sub-group of migraines, some believe that the stroke-like damage that is frequently associated with this group of headaches places it in a different category and should be treated very differently from the typical migraine.
Treatment
Unfortunately, the vertigo component of migraines is extremely resistant to standard treatment. The triptan class of drugs is relatively ineffective. Also, the standard anti-vertigo drugs like meclizine and phenergan also do not work well.
A Better Method For Migraine Relief
There is another option to relieve migraine pain – a migraine cure. Cure the migraine and never worry about migraine-associated vertigo again.
Recent reports indicate migraine headaches can indeed be totally abolished – as a number of elite medical clinics catering to women have testified. Under their treatment protocols, migraines are completely eliminated in 80% of their patients.
These successes are limited to women only, as addressing a woman’s hormones is the basis of the cure. Some clinics have published their treatment protocols and even made them available to the public.
APPLIES TO:
• migraine
• migraines
• migraine headaches
• headaches
• migraine headache
• migraine headache relief
• migraine relief
• headache treatment cure
• women's health
• birth control pills
• oral contraceptives
Migraine is a disease characterized by periodic headaches, but patients often experience other symptoms, including dizziness. In some patients, dizziness can be the only symptom. The dizziness associated with migraines is called vertigo.
Vertigo is basically a sensation of a room spinning around you, while at rest. Nausea and sometimes vomiting is always associated with vertigo.
Motion sickness is a common migraine accompaniment as well. Most studies report about 50% of patients with migraines have motion sickness. Patients with migraine-associated vertigo often provide a long history of motion intolerance during car, boat, or air travel or all three. People with migraines are, in general, more sensitive to motion of the environment and to busy environments.
The symptoms of migraine-associated vertigo are variable and may feel like a room spinning at rest (true vertigo), a constant feeling of imbalance, and/or dizziness associated primarily when moving and not at rest. Symptoms directly associated with a migraine headache can occur prior to the onset of headache or during a headache.
Vertigo Without Headaches
It is also quite common to experience vertigo during a headache-free interval. As such, many patients who experience migraine-associated vertigo will experience dizziness as the main symptom even in the absence of a headache! In fact, most patients with migraine-associated vertigo have dizziness that occurs independently of the headache.
This last condition of someone experiencing vertigo without any headache confuses doctors and patients alike. It is far more common than thought and most of the time is a missed diagnosis and thereby a missed opportunity for treatment.
Prevalence of Migraine-Associated Vertigo
Reports indicate that 27-42% of all migraine patients report episodic vertigo. What is interesting is that about a third (about 36%) of these patients experienced vertigo during headache-free periods. The remainder experienced vertigo either just before or during the headache. The incidence of vertigo during the headache period was higher in patients with aura as opposed to those without aura.
Duration:
The vertigo symptoms may last for a few minutes or may be continuous for several weeks or even for months! In women, there is a strong association of dizziness occurring within the menstrual cycle.
The duration of the vertigo can also be quite variable. The frequencies of different durations of vertigo spells in migraine-associated vertigo are as follows:
o 7% experience vertigo for a duration of seconds.
o 31% experience vertigo for minutes to up to 2 hours.
o 5% have vertigo for 2-6 hours.
o 8% have vertigo for 6-24 hours.
o 49% experience vertigo for longer than 24 hours.
What Causes the Vertigo Associated with Migraines?
The most commonly accepted theory regarding the pathophysiology of migraine-associated vertigo is the Cortical Spreading Depression theory (CSD). Multiple authors propose that episodes of dizziness are similar to that of a migraine aura or are actually part of the aura.
But since only about 20% of migraine sufferers actually experience an aura, researches attribute the vertigo as part of a fluctuation of nerve cell ion channels. Recent understandings in a particular type of migraine – Familial Hemiplegic Migraine (FHM) have shown two genes responsible for controlling ion flow across nerve cell membranes.
These two genes affect changes in calcium, sodium and potassium channels. This alters the electrical conduction potentials of nerve cells. The result is a transient wave front that suppresses central neuronal activity. This depression spreads in all directions from its site of origin. These changes result in a reduction in cerebral blood flow in the areas of spreading depression.
Two authors have suggested that when dizziness is unrelated to headache, the dizziness occurs from the release of neuropeptides, including substance P, neurokinin A, calcitonin and gene–related peptide [CGRP].
No single hypothesis explains the headache or dizziness process in migraine at this time. Thus, the causes of the symptoms of migraine remain controversial.
Meniere’s Disease
There is another relatively common form of vertigo called Meniere’s Disease. Meniere’s Disease is not related to migraines at all. It has a classic triad of vertigo, hearing loss and tinnitus (ringing of the ears). The vertigo of Meniere’s Disease is frequently confused with migraine-associated vertigo.
Fortunately, the vertigo associated with the more common forms of migraines rarely have any hearing loss and also does not have much in the way of tinnitus.
Basilar Migraines
The is one ominous variant of migraine headaches called Basilar Migraines (or also known as Bickerstaff ‘s syndrome) which is a cross between a migraine and occasionally ends up in a stroke. Some features of Basilar Migraines include vertigo, hearing loss and tinnitus. Up to 80% of patients with Basilar Migraine have been reported to have sensorineural hearing loss.
So in the case of the Basilar Migraines, the vertigo might be indistinguishable from Meniere’s Disease during the headache-free intervals. Otherwise the presence of the headache would lend it toward the migraine component and should be treated as a migraine.
Clearly, Basilar Migraines are a more pernicious variety of migraine headache. Even though Basilar Migraines are classified as a sub-group of migraines, some believe that the stroke-like damage that is frequently associated with this group of headaches places it in a different category and should be treated very differently from the typical migraine.
Treatment
Unfortunately, the vertigo component of migraines is extremely resistant to standard treatment. The triptan class of drugs is relatively ineffective. Also, the standard anti-vertigo drugs like meclizine and phenergan also do not work well.
A Better Method For Migraine Relief
There is another option to relieve migraine pain – a migraine cure. Cure the migraine and never worry about migraine-associated vertigo again.
Recent reports indicate migraine headaches can indeed be totally abolished – as a number of elite medical clinics catering to women have testified. Under their treatment protocols, migraines are completely eliminated in 80% of their patients.
These successes are limited to women only, as addressing a woman’s hormones is the basis of the cure. Some clinics have published their treatment protocols and even made them available to the public.
APPLIES TO:
• migraine
• migraines
• migraine headaches
• headaches
• migraine headache
• migraine headache relief
• migraine relief
• headache treatment cure
• women's health
• birth control pills
• oral contraceptives
Migraine Headaches 3
Almost every article you read about migraine headaches mentions something called the “classical migraine.” But how many people really have this “classical” condition?
Migraines are typically divided into two major categories: Classical and common.
Classical migraine headaches typically start with an “aura” lasting 10 minutes to an hour before the headache itself begins.
The aura frequently is a sensation of flashing lights, blind spots, visual zig zag lines, tingling or even numbness. Other classic symptoms may include confusion, slurred speech or weakness in an arm or leg. (Please see our previous article: “The Migraine Aura – Tricks From The Brain” for more information.)
Common migraine headaches are not preceded by an aura. These headaches generally just arrive without warning. They may start off with just a mild pain, but then quickly intensify over a matter of minutes. But the headache in a common migraine can be just as painful as the classical variety - regardless of whether the sufferer had an aura or not.
How Common Are Migraines?
Depending on whose statistics you use, migraine headaches are found in about 10% of the population. Since women officially have three times more incidences of headaches than men, the number of females experiencing migraines approaches18%. As women approach the age of 35, the peak incidence of migraines increases to nearly 35% - nearly one in three!
These figures are consistent worldwide – and not just limited to the United States.
Earlier studies raised the issue that Asians experience far few migraines than Westerners. However, recent surveys seem to refute this finding. This is interesting – because it would seem to indicate that migraines are a universal human condition and not cultural or developmental phenomena.
It’s also estimated another 5% of the worldwide population have migraine headaches but don’t know it! These people have either incorrectly self-diagnosed their condition - or had their pain misdiagnosed as tension or sinus headaches.
Of all the people who experience migraine headaches, properly diagnosed or not, about 20% are supposed to have the “classical” aura type of migraine.
Migraines Much More Common Than Realized
In real practice however, my observations have shown migraine headaches are much more common in the general population than formerly reported. Twice as many women as previously thought, about 1 in 5, will experience at least one migraine in their life. But of those women, very few of them experience an aura.
Furthermore, official statistics indicate that 60-70% of women experience “hormonal” headaches - headaches based on their monthly cycle.
Again, my actual experience is that far more women experience migraine headaches to menstrual cycle changes than officially recognized. In all likelihood, this is due to external stimuli affecting the body – such as birth control pills and certain prescription medications.
Migraine Headaches Swelling Worldwide
What’s even worse, migraine headaches seem to be increasing worldwide, especially over the last 50 years, and particularly in women. Preliminary observations indicate that virtually every family in America has at least one female member experiencing migraine headaches.
The Centers for Disease Control reported a 60-percent increase in the incidence of migraine headaches from 1980 to 1989. A Mayo Clinic study released in 1999 showed similar findings where migraine headaches in women increased 56 percent during the 1980s while the incidence of migraine headaches in men increased 34 percent during the same period.
The clinic’s author speculated the reasons were four-fold:
* “Stress “
* A rise in the number of single-parent households
* An increase in the number of women in the workforce
* An increase in women who are dieting for weight loss
With all due respects to the Mayo Clinic, the Women’s Health Institute of Texas believes in alternate explanations for the increasing incidence of migraines:
* Increased use of birth control pills since 1960
* Progressive exposure to “xenoestrogens” over the last 50 years
* Worsening dietary habits over the last 25 years
All three reasons certainly account for the disturbing uptrend in women’s migraines. The last two reasons apply to men just as well as to women. The entire population is being exposed to high levels of xenoestrogens, and the dietary habits of both men and women have progressively declined - as evidenced by the ever-rising numbers in obesity.
What are Xenoestrogens?
Xenoestrogens are chemicals exhibiting estrogen-like activity. “Xeno” means foreign, so xenoestrogen simply means “a foreign estrogen.” There are tens of thousands of chemicals that exert hormonal effects, with xenoestrogens exerting estrogenic effects.
Examples of xenoestrogens include pesticide residues on fruits and vegetables, hormone additives to grain fed beef and “gas off” from plastic water bottles.
Too much exposure to estrogen can cause numerous medical difficulties, manifesting as a myriad of “female” problems in women. These range from Depression to uterine fibroids to breast cancer. In men, these can range from gynecomastia (development of breast tissue) to prostate cancer.
Incidentally, this problem doesn’t just involve humans. A recent article in “The Week” magazine cites estrogen-like contaminants being responsible for male fish in Maryland’s Potomac River actually carrying eggs! What used to be a one in a million abnormality now affects 80% of the smallmouth bass population.
APPLIES TO:
• migraine
• migraines
• migraine headaches
• headaches
• migraine headache
• migraine headache relief
• migraine relief
• headache treatment cure
• women's health
• birth control pills
• oral contraceptives
Migraines are typically divided into two major categories: Classical and common.
Classical migraine headaches typically start with an “aura” lasting 10 minutes to an hour before the headache itself begins.
The aura frequently is a sensation of flashing lights, blind spots, visual zig zag lines, tingling or even numbness. Other classic symptoms may include confusion, slurred speech or weakness in an arm or leg. (Please see our previous article: “The Migraine Aura – Tricks From The Brain” for more information.)
Common migraine headaches are not preceded by an aura. These headaches generally just arrive without warning. They may start off with just a mild pain, but then quickly intensify over a matter of minutes. But the headache in a common migraine can be just as painful as the classical variety - regardless of whether the sufferer had an aura or not.
How Common Are Migraines?
Depending on whose statistics you use, migraine headaches are found in about 10% of the population. Since women officially have three times more incidences of headaches than men, the number of females experiencing migraines approaches18%. As women approach the age of 35, the peak incidence of migraines increases to nearly 35% - nearly one in three!
These figures are consistent worldwide – and not just limited to the United States.
Earlier studies raised the issue that Asians experience far few migraines than Westerners. However, recent surveys seem to refute this finding. This is interesting – because it would seem to indicate that migraines are a universal human condition and not cultural or developmental phenomena.
It’s also estimated another 5% of the worldwide population have migraine headaches but don’t know it! These people have either incorrectly self-diagnosed their condition - or had their pain misdiagnosed as tension or sinus headaches.
Of all the people who experience migraine headaches, properly diagnosed or not, about 20% are supposed to have the “classical” aura type of migraine.
Migraines Much More Common Than Realized
In real practice however, my observations have shown migraine headaches are much more common in the general population than formerly reported. Twice as many women as previously thought, about 1 in 5, will experience at least one migraine in their life. But of those women, very few of them experience an aura.
Furthermore, official statistics indicate that 60-70% of women experience “hormonal” headaches - headaches based on their monthly cycle.
Again, my actual experience is that far more women experience migraine headaches to menstrual cycle changes than officially recognized. In all likelihood, this is due to external stimuli affecting the body – such as birth control pills and certain prescription medications.
Migraine Headaches Swelling Worldwide
What’s even worse, migraine headaches seem to be increasing worldwide, especially over the last 50 years, and particularly in women. Preliminary observations indicate that virtually every family in America has at least one female member experiencing migraine headaches.
The Centers for Disease Control reported a 60-percent increase in the incidence of migraine headaches from 1980 to 1989. A Mayo Clinic study released in 1999 showed similar findings where migraine headaches in women increased 56 percent during the 1980s while the incidence of migraine headaches in men increased 34 percent during the same period.
The clinic’s author speculated the reasons were four-fold:
* “Stress “
* A rise in the number of single-parent households
* An increase in the number of women in the workforce
* An increase in women who are dieting for weight loss
With all due respects to the Mayo Clinic, the Women’s Health Institute of Texas believes in alternate explanations for the increasing incidence of migraines:
* Increased use of birth control pills since 1960
* Progressive exposure to “xenoestrogens” over the last 50 years
* Worsening dietary habits over the last 25 years
All three reasons certainly account for the disturbing uptrend in women’s migraines. The last two reasons apply to men just as well as to women. The entire population is being exposed to high levels of xenoestrogens, and the dietary habits of both men and women have progressively declined - as evidenced by the ever-rising numbers in obesity.
What are Xenoestrogens?
Xenoestrogens are chemicals exhibiting estrogen-like activity. “Xeno” means foreign, so xenoestrogen simply means “a foreign estrogen.” There are tens of thousands of chemicals that exert hormonal effects, with xenoestrogens exerting estrogenic effects.
Examples of xenoestrogens include pesticide residues on fruits and vegetables, hormone additives to grain fed beef and “gas off” from plastic water bottles.
Too much exposure to estrogen can cause numerous medical difficulties, manifesting as a myriad of “female” problems in women. These range from Depression to uterine fibroids to breast cancer. In men, these can range from gynecomastia (development of breast tissue) to prostate cancer.
Incidentally, this problem doesn’t just involve humans. A recent article in “The Week” magazine cites estrogen-like contaminants being responsible for male fish in Maryland’s Potomac River actually carrying eggs! What used to be a one in a million abnormality now affects 80% of the smallmouth bass population.
APPLIES TO:
• migraine
• migraines
• migraine headaches
• headaches
• migraine headache
• migraine headache relief
• migraine relief
• headache treatment cure
• women's health
• birth control pills
• oral contraceptives
Migraine Headaches 2
Migraine headaches generally come in two forms: With and without auras. The headaches themselves can be equally painful – whether or not an aura is present.
Statistics indicate that only about 20% of migraine sufferers actually experience these auras. However, I’ve actually observed that the prevalence of aura type migraines is substantially less than that.
What Is A Migraine Aura?
The aura is a distortion in perception. Most often a migraine aura is a visual alteration or other sensory phenomena occurring just before the pain phase of a migraine headache starts. The aura also typically ends before the headache itself begins.
Symptoms associated with auras may include flashing lights, geometric patterns, or distorted vision.
However, some people may have non-visual auras involving hearing sounds (usually buzzing), olfactory auras involving smelling odors, or tactile auras that manifest like a physical touching sensation.
Characteristics Associated With Auras Include:
- Flashing lights
- Wavy or zigzagging lines
- Visual spots or other shapes
- Blind spots or partial loss of sight
- Blurry vision
- Olfactory hallucinations, or the smelling of aromas that aren’t really there
- Tingling feeling or numbness about the face or extremities
- Difficulty speaking or forming words
- Confusion
- Vertigo (dizziness)
- Partial and temporary paralysis
- Hearing loss
- Reduced sensation to touch
- Hypersensitivity to feel and touch
Migraine auras normally lasts from 20 minutes to an hour; however some sufferers have been known to experience aura symptoms lasting up to two days. Migraine aura symptoms can and do vary tremendously from one migraine sufferer to the next.
“Negative” and “Positive” Symptoms
The most commonly reported aura consists of flashing lights or zigzagging lines, known as the so-called “positive” symptoms.
Partial or total visual field loss or vision blackouts are called “negative symptoms”.
A combination of so-called “negative symptoms” (such as vision loss) with the “positive symptoms” (like zigzagging lines) make up the typically distinctive features of a migraine aura.
Vision blackouts - the “negative symptoms” - are caused by a depression of nerve activity. On the other hand, zigzagging lines are caused by hyperactivity in the nerve cells.
Cortical Spreading Depression (CSD)
Special imaging and magnetic brainwave studies strongly suggest that Cortical Spreading Depression (CSD) forms the biological basis for the “negative symptoms” of a migraine aura.
From studying a particular type of migraine - Familial Hemiplegic Migraine (FHM) - recent findings have shown two genes are responsible for causing this symptom. These genes - which control the ion flow of calcium, sodium and potassium to the nerve cells - are damaged in people inclined to this type of migraine. It’s believed this genetic mutation makes a person’s neurons susceptible to CSD.
In essence, the nerve cells (or neurons) don’t get properly “recharged” – resulting in diminished or depressed neural activity. Whatever the reason, this reduced activity slows down normal body functioning. If the affected neuron complex happens to control the sight centers (visual cortex) then visual disturbances or losses may occur.
However, as these neurons begin to react to or recover from the CSD, they may become hyper excitable, resulting in visual phenomena such as flashing lights and zig zag lines. (It’s sort of like the neuron’s compensate by rebounding and going into overdrive!)
This hyper excitability then activates the major nerve complex behind the eye (trigeminal nerve). This initiates migraine headaches by activating the highly pain-sensitive “dura mater” - the membrane sheet wrapping around the brain.
Calcium Channel Blocker Drugs
Researchers speculated that blocking the ion channels flowing through the neuron cell membranes would help reduce migraine pain. Some suggested using drugs to slow down and block these channels – for example “calcium channel blocker” medications.
Calcium channel blockers (such as verapamil) are widely used to treat heart disease and high blood pressure. They’re also now extensively used to prevent migraine headaches. Unfortunately, their effectiveness in migraine prevention is minimal at best.
A Better Method
There is another option – a migraine cure. Cure the migraine and never worry about their associated auras or pain again.
Recent reports indicate migraine headaches can indeed be totally abolished – as a number of elite medical clinics catering to women have testified. Under their treatment protocols, migraines are completely eliminated in 80% of their patients.
These successes are limited to women only, as addressing a women’s hormones is the basis of the cure. Some clinics have published their treatment protocols and even made them available to the public.
APPLIES TO:
• migraine
• migraines
• migraine headaches
• headaches
• migraine headache
• migraine headache relief
• migraine relief
• headache treatment cure
• women's health
• birth control pills
• oral contraceptives
Migraine Headaches
Prior to the introduction of a new class of medications in the 1990’s, medical management of migraines was limited to either narcotics (which are addictive) or just not very effective. With the introduction of a class of medications called triptans, migraine headache management was revolutionized.
• migraine
• migraines
• migraine headaches
• headaches
• migraine headache
• migraine headache relief
• migraine relief
• headache treatment cure
• women's health
• birth control pills
• oral contraceptives
The more technical name for this class of medications is selective serotonin receptor agonists. Triptans are not pain medications as we traditionally think of them. Traditional pain medications don't end the pain. They simply increase our tolerance to it -- temporarily. Unless the migraine attack has run its course while a pain medication is working, the symptoms will return when the pain medication wears off.Triptans are termed abortive migraine medications. They cannot prevent migraines. They are used to abort a migraine attack in an effort to stop the attack itself and the associated symptoms.
The effect on the blood vessels is considerable in that they seem to tighten up or vasoconstrict arteries. This is consistent with observed vasodilatation or opening up of the arteries during a migraine headache attack.
The potential danger of this class of medications is that someone who has borderline blood flow to the heart or brain, for example in ischemic heart disease, is at risk for a full blown heart attack or stroke if these medications are taken. Most migraine sufferers are younger so this is generally not that great a concern for the vast majority of people with migraine headaches.
With the first medication called Imitrex®, made by Glaxo-Smith-Kline, the triptan revolution swept across migraine headache management. The initial product was an injectible medication and had a quick onset of action. Many people were relieved relatively quickly and thought it was a godsend, despite the steep price.
Imitrex® was also sold under the name Imigran®. It also became available in a tablet and nasal spray forms. Soon after Imitrex came to the market, other drug companies began rolling out their own triptan medications. Imitrex® had been followed by Maxalt®, Zomig®, Amerge®, Avert®, Frova® and Relpax®. All of the other manufacturers made their triptans into a pill form, with Maxalt® and Zomig® having a dissolvable pill.
The various routes of administration are important. For example, the injectible Imitrex® has the fastest onset of action and to this day still provides the greatest amount of relief once the headache strikes. The dissolvable forms are for those people whose nausea is so significant that they are unable to keep down a swallowed pill. The nasal spray is also an option to bypass the stomach.
Side effects to watch for include chest pain, throat pain or abdominal pain. The reason why these pains are important to look for is that they may indicate a reduction in blood supply to the heart or major organs of the body. People with angina pectoris or ischemic heart disease are advised to not take these medications.
Secondary side effects include shortness of breath, wheezing, heart palpitations, facial or eyelid swelling, skin rashes, tingling and flushing, drowsiness, dizziness, dry mouth, muscle pain, feeling tired and sick. The tingling is a particularly common observation.
The good news is that the secondary side effects are not going to kill you. Most people are willing to trade a reduction in the migraine headache attack for a little discomfort.
Another medication that is still commonly used, even though it is not part of the triptan class of medication is called ergotamine, or more precisely, dihydroergotamine (brand names Migranal®, DHE-45®). This medication works to constrict blood vessels, similar in action to the triptans. Side effects are similar with the same warnings to those people with bad hearts.
Waiting for the headache to start and subsequent rushing to take a triptan or ergotamine medication is the most common method of migraine headache management in those people who do not experience a high frequency of headaches.
For those who are plagued with frequent headaches, another major approach involving medication is through an attempt of preventive or prophylactic measure to stop the headaches from coming in the first place.
This method has shown to be very disappointing. It barely exceeds results found in placebo methods.
The most common attempt at migraine prevention is the use of beta-blockers. Propranolol (Inderal®) is the most commonly prescribed beta blocker for this purpose.
Anti-depressant medications are also extremely commonly used. The thinking here is that there is some relationship with serotonin levels, which anti-depressants do have some type of effect on. I have never seen anyone with migraine headaches benefit from anti-depressants.
The medical profession, as a rule, is generally pretty quick to prescribe anti-depressants for virtually any condition which they don’t understand. Doctors particularly like to prescribe anti-depressants for women.
Calcium channel blockers like verapimil are occasionally prescribed as a preventative. Verapimil is used primarily to treat high blood pressure and is also used to treat irregular heart rhythms.
If a migraine sufferer also has high blood pressure or an irregular heart rhythm, many doctors will prescribe verapimil to treat all of these conditions at the same time. One drug treats multiple conditions. Otherwise, calcium channels do not tend to be used for migraine treatment.
Rarely, the drug methysergide will be prescribed. There are some pretty scary side effects associated with this drug, and it is nowhere near the top of the list in being prescribed any more.
Finally, in the traditional prevention class, a whole new set of medications that had been used to treat seizure disorders has been tried. Depakote®, Neurontin® and Topamax® are the top three anti-seizure medications now being used for migraine headache prophylaxis.
All three of those medications have potentially significant side effects and are frequently not tolerated by people long-term. Some people do benefit significantly, however.
Pain Management
Finally, there is the general pain management approach to migraine headaches. This approach is not specific to migraines, but to pain in general.There are basically two types of pain medications: Non-narcotic and narcotic pain medication.
Non-narcotic pain medications consist of anti-inflammatory medications called NSAIDS. These are the aspirin-like compounds found in prescription strength and over the counter at a local pharmacy. The public is well versed with the brand names like Motrin®, Nuprin® and Aleve®. I will not go into any further detail here. Another major non-narcotic medication, but is technically not an NSAID, is Tylenol®. Again, the public is knowledgeable about this drug.
The narcotic pain medications are the other pain management method to migraine headaches. Vicodin® and Lorcet® are perhaps the most familiar first-line narcotic pain medications. There are tighter prescription controls on doctors for other narcotics like Percodan®, Darvon®, Equigesic®, and Oxycontin®, just to name a few. There are many, many narcotic medications available.
Narcotics are almost never advisable unless there is an emergency room situation whereby this is the initial presentation of a migraine headache or a dramatic worsening compared to past headaches. Some unfortunate sufferers of cluster headaches require narcotics. Many have committed suicide.
Once you go down the road of requiring narcotic pain medications for a medical condition that does not resolve, addiction and tolerance is a near certainly. There are numerous political and legal implications for both the doctor and the patient when this occurs.
Virtually all 50 state boards of medicine that regulate doctors and grant their licenses to practice medicine are taking a strong look at narcotic-prescribing habits of doctors. This is why doctors are extremely reluctant to prescribe narcotics almost under any situation. As a result, many people who require these medications cannot obtain them.
Conclusion
In summary, traditional medical management of migraine headaches is frankly ineffective and burdensome. Only with the advent of triptan medication class just 15 years ago have there been some strides made in this regard.
Unfortunately, the triptans, which are indeed helpful, are only taken AFTER a migraine headache has started. Frequently they don’t help to completely eliminate migraine attack symptoms. It is not unusual for these medications to get “tolerated” and lose their effectiveness in the same person over time.
Switching brands of triptans in order to find the brand that proves to be the most effective one is the rule. Even though they do help, this is still a fairly miserable lifestyle. The waiting for the next migraine headache is always lurking, particularly when noone knows if this next migraine headache is going to respond to the latest triptan drug.
None of the other “traditional” approaches to migraine headache management are effective. Unfortunately, there is essentially no good mainstream preventative drug out there that works. Traditional pain medications with narcotics or NSAIDS are simply ineffective and just not the right way to treat this condition.
Something is clearly missing in this picture. What is needed is a CURE, not a band-aid. If someone can nail down the actual reason why migraine headaches are contracted in the first place and find something to eliminate that condition, then we won’t have to worry about all the other techniques that are aimed at combating the outbreaks.
Sure enough, if we found something that simply eliminates the cause of migraine headaches to begin with then we should definitely apply that knowledge. Almost quite by accident, I have discovered in my practice an association between migraine headaches and the relative deficiencies of certain sex hormones.
Replacing the deficient hormones and satisfying the deficit has led to a complete resolution and cure of the migraine headaches in patient after patient. Admittedly, we don’t necessarily understand the exact biochemical mechanism as to why and how exactly do migraines result from a hormone deficiency.
But achieving complete cure in 80% of the times, my patients don’t seem to mind the fact that we don’t have all of the answers. They are pain-free and completely cured and are quite happy in that knowledge. What this information offers is a path to complete cure to your migraine headaches and even cluster headaches. It is simple, natural, safe and very inexpensive with zero side effects.
The information contained is known to all doctors, because they learned it in their first year of medical school – and most have since forgotten it. Doctors (and I was part of that mindset for many years) are trained to prescribe drugs. That is what they do and all they know. Thanks to the US patent laws, these drugs are never natural or bio-identical. They are all chemical compounds, foreign to the body and fraught with side effects.
APPLIES TO:• migraine
• migraines
• migraine headaches
• headaches
• migraine headache
• migraine headache relief
• migraine relief
• headache treatment cure
• women's health
• birth control pills
• oral contraceptives
Wednesday, April 9, 2008
Apparel Articles
Corduroy is a textile made of twisted fibres that are woven in a form parallel to one another which makes the 'cord' in the fabric. The word 'corduroy' is derived from the word, 'corde du roi" which means 'cord or cloth of the king'. It is a ridged form of velvet. It is considered as a long-lasting cloth. Clothes from corduroy are preferred by people..
Apparel supply chain is a network of distribution options performing various functions starting from the procurement of raw materials to the transformation into finished products, and its distribution to customers. In olden days, various divisions of the present supply chain like procurement of raw materials, planning, manufacturing, and...
Clothing is a form of non-verbal communication. Clothing has a powerful communicating effect, and tells 'something' about the person wearing it, and creates an impression in the minds of others. Different types of clothes suit different surroundings. Environmental factors affect the choice of clothing. Clothes with antistatic and aesthetic properties are...
This study analyzes the criticality of design factors that contribute to discernable differential in the experiences of goal-focused shoppers on dress model Web sites. Focused on the apparel industry, the study examines factors of accessibility and convenience, availability of information, lack of sociality, media richness, and product.
The science of clothing has evolved drastically. Innovations in the field of textiles are now way ahead. A niche in the field of elite sports wear is apparels that have entered our lives and will monitor our heart beats and other vital signs. Apparels are manufactured with textile based electrodes to receive biophysiological signals from the user. Textronics Inc, has developed...
Corn is used; not just for eating but the fibres acquired from it is also used to manufacture pretty garments. This is a natural renewable fibre and does not come from petro chemicals. Dextrose, a material extracted from corn amylum is fermented to make lactic acid. Water from this substance... 
Heat is required for the survival of any living being. Human body should be able to produce and retain heat depending on the ambient external temperature. When temperatures drop very low during winter it becomes a challenge to remain safe and warm. ThermoLogic Apparel is the latest advancement in heated clothing which enables the wearer to have control over the environment...
Does the government really have a plan for South Africa’s clothing and textile industry sectors? Recent historical analysis reflects that government policies are full of contradictions leaving one to wonder if it is serious about finding equitable and sustainable solutions to "save the industry...
Fashion is now developing with a richness and creativity that is remarkable. Changes in the fashion world are constant and always include an inspiration of the past. Fads change over the years and some even make a comeback. Latest trends of today may be a redefined fad of the past...
A simple and low cost equipment for measuring fabric hand has been designed. This method is based on the nozzle extraction method, which measures the force generated while extracting a circular fabric specimen through a nozzle. Instrument gives a single value (specific handle force-SHF), which is easy to determine and understand...
A button is a small plastic or metal knob, usually attached with clothing to secure an opening in the garment or can also be used for decorative purposes. Its name originates from the French word 'bouton' meaning a metal piece to connect different parts of a garment. Its legend can be traced back to the primeval ages. Ancient p... Researchers of the Auckland University of Technology have discovered recently that there is a big change in the way manufacturers use measurement techniques to take the customers body measurements. During the past decades, there has been a vast change in the living style, demography, body size and shape of individuals, but the measurement techniques did not keep pace...
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